Jeremy Strong, Dr. Francis Collins

1 Supreme Court Justice Ketanji Brown Jackson, KAYTRANADA, Rayvn Lenae, Channel Tres 2 Curtis "50 Cent" Jackson, Jack Lowden 3 Stephen Curry, Senator Mark Kelly 4 Jim Parsons, Natasha Rothwell 5 John Dickerson, Tems 6 Samuel L. Jackson, Amy Ryan 7 Jeff Bridges, Evie McGee Colbert 8 Jeremy Strong, Dr. Francis Collins 9 Rachel Maddow, Shaboozey 10 Anderson Cooper, Sting 11 Justin Trudeau, RuPaul Charles 12 Kate Winslet, Jude Law 13 Bill Gates, Jane Goodall 14 Sarah Silverman, Chris Stapleton 15 Don Cheadle, Malcolm Gladwell 16 Chris Hayes, Brittany Howard 17 Andrew Garfield, Ina Garten 18 Chris Wallace, Yotam Ottolenghi, Justin Hartley 19 Vice President Kamala Harris 20 Kathy Bates, Pamela Anderson, Grace Bowers 21 Jason Segel, Rep. Jasmine Crockett 22 Stanley Tucci, Harvey Guillén 23 Bob Woodward, Wyatt Flores 24 Brian Cox, Yulia Navalnaya 25 Sen. John Fetterman, Alfonso Cuarón 26 Anna Kendrick, Matty Matheson 27 Jonathan Alter, JHAYCO, Julia Louis-Dreyfus 28 Robin Wright, Nicole Scherzinger 29 Tom Hanks, Rachel Zegler, Jack Antonoff, the cast of "Romeo + Juliet" 30 Kieran Culkin, Ta-Nehisi Coates 31 Seth Meyers, Mohanad Elshieky 32 Governor Tim Walz, John Oliver 33 John Dickerson, Lenny Kravitz 34 Paul Bettany, Mike Birbiglia, Robert Zemeckis 35 Javier Bardem, Chris Evans, Curtis "50 Cent" Jackson 36 People's "Sexiest Man Alive" reveal, Francis Ford Coppola 37 Zoe Saldaña, Ken Burns 38 Billy Bob Thornton, Sharon Horgan 39 Josh Brolin, Kacey Musgraves 40 Bill Clinton, Kacey Musgraves 41 Paul Mescal, Elvis Costello, T Bone Burnett, the Coward Brothers 42 Rep. Hakeem Jeffries, Jeffrey Wright 43 Daniel Craig, Auli'i Cravalho 44 Selena Gomez, José Andrés 45 Anderson Cooper, Andy Cohen, Doechii 46 Kate McKinnon, Peter Sarsgaard, Ben Folds